Invention Grant
- Patent Title: Triazole compounds that modulate Hsp90 activity
- Patent Title (中): 调节Hsp90活性的三唑化合物
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Application No.: US14685178Application Date: 2015-04-13
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Publication No.: US09206162B2Publication Date: 2015-12-08
- Inventor: Lijun Sun , Weiwen Ying , Junghyun Chae , Teresa Kowalczyk-Przewloka , Shijie Zhang , Dinesh U. Chimmanamada , Kevin Paul Foley , Zhenjian Du , Hao Li , David James , Howard P. Ng , Zachary Demko , Dan Zhou , Shuzhen Qin
- Applicant: Synta Pharmaceuticals Corp.
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: McCarter & English, LLP
- Agent Steven G. Davis; Mei Bai
- Main IPC: C07D403/04
- IPC: C07D403/04 ; C07D401/14 ; C07D413/14 ; C07D401/04 ; C07D405/14

Abstract:
The present invention relates to substituted triazole compounds and compositions comprising substituted triazole compounds. The invention further relates to methods of inhibiting the activity of Hsp90 in a subject in need thereof and methods for preventing or treating hyperproliferative disorders, such as cancer, in a subject in need thereof comprising administering to the subject a substituted triazole compound of the invention, or a composition comprising such a compound.
Public/Granted literature
- US20150266858A1 TRIAZOLE COMPOUNDS THAT MODULATE HSP90 ACTIVITY Public/Granted day:2015-09-24
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