Invention Grant
US09206171B2 6-{2 -[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole bis-dihydrogenphosphate salt (1:2)
有权
6- {2- [1-（6-甲基-3-哒嗪基）-4-哌啶基]乙氧基} -3-乙氧基-1,2-苯并异恶唑二磷酸二氢磷酸盐（1:2）
![6-{2 -[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole bis-dihydrogenphosphate salt (1:2)](/docs/US/2015-12-08/US09206171B2/abs.jpg.600x600.jpg)
- Patent Title: 6-{2 -[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole bis-dihydrogenphosphate salt (1:2)
- Patent Title (中): 6- {2- [1-（6-甲基-3-哒嗪基）-4-哌啶基]乙氧基} -3-乙氧基-1,2-苯并异恶唑二磷酸二氢磷酸盐（1:2）
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Application No.: US14023280Application Date: 2013-09-10
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Publication No.: US09206171B2Publication Date: 2015-12-08
- Inventor: Jane Ryan , Margaret Anne Butt
- Applicant: Biota Scientific Management Pty Ltd
- Applicant Address: AU Notting Hill, Victoria
- Assignee: BIOTA SCIENTIFIC MANAGEMENT PTY LTD
- Current Assignee: BIOTA SCIENTIFIC MANAGEMENT PTY LTD
- Current Assignee Address: AU Notting Hill, Victoria
- Agency: Stites & Haribison, PLLC
- Agent B. Aaron Schulman, Esq.
- Main IPC: C07D237/20
- IPC: C07D237/20 ; C07D211/22 ; C07D261/20 ; C07D413/14 ; A61K31/501 ; A61K45/06
![6-{2 -[1-(6-methyl-3-pyridazinyl)-4-piperidinyl]ethoxy}-3-ethoxy-1,2-benzisoxazole bis-dihydrogenphosphate salt (1:2)](/abs-image/US/2015/12/08/US09206171B2/abs.jpg.150x150.jpg)
Abstract:
This invention relates to antiviral agents, in particular to salts useful in the treatment of infections caused by Picornaviridae, such as human rhinovirus (HRV) and methods for their preparation. In one embodiment, the invention relates to a bis-dihydrogenphophate salt having the formula: The invention also relates to the use of these salts in the treatment of picornavirus infections. The salts of this invention are especially suitable for use in the treatment of HRV, however it is to be understood that the invention is also applicable to other viruses of the picornavirus family.
Public/Granted literature
- US20140179710A1 ANTIVIRAL SALTS Public/Granted day:2014-06-26
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