Invention Grant
US09206186B2 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity for the treatment of inflammatory or immunological disorders
有权
具有CCR3拮抗活性的2-苯氧基和2-苯基磺酰胺衍生物，用于治疗炎性或免疫学障碍
- Patent Title: 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity for the treatment of inflammatory or immunological disorders
- Patent Title (中): 具有CCR3拮抗活性的2-苯氧基和2-苯基磺酰胺衍生物，用于治疗炎性或免疫学障碍
-
Application No.: US14010354Application Date: 2013-08-26
-
Publication No.: US09206186B2Publication Date: 2015-12-08
- Inventor: Yingfu Li , Kevin Bacon , Hiromi Sugimoto , Keiko Fukushima , Kentaro Hashimoto , Makiko Marumo , Toshiya Moriwaki , Noriko Nunami , Naoki Tsuno , Klaus Urbahns , Nagahiro Yoshida
- Applicant: AXIKIN PHARMACEUTICALS, INC.
- Applicant Address: US CA San Diego
- Assignee: AXIKIN PHARMACEUTICALS, INC.
- Current Assignee: AXIKIN PHARMACEUTICALS, INC.
- Current Assignee Address: US CA San Diego
- Agency: Jones Day
- Priority: EP03006293 20030324
- Main IPC: C07D453/02
- IPC: C07D453/02 ; C07D487/02 ; C07D487/08 ; A61K31/439 ; C07D487/04 ; C07C311/29 ; C07D207/12 ; C07D207/14 ; C07D207/16 ; C07D207/40 ; C07D207/404 ; C07D207/48 ; C07D211/54 ; C07D223/12 ; C07D241/04 ; C07D243/08 ; C07D257/04 ; C07D295/13 ; C07D295/22 ; C07D295/26 ; C07D303/06 ; C07D303/36 ; C07D401/04 ; C07D401/06 ; C07D401/14 ; C07D403/06 ; C07D403/12
Abstract:
Provided herein are 2-phenoxy- and 2-phenylsulfonamide derivatives with CCR3 antagonistic activity. These compounds are useful for the treatment of diseases associated with CCR3 activity, including but not limited to, atopic dermatitis, allergic rhinitis, rheumatoid arthritis, Grave's disease, HIV infection, Alzheimer's disease, atherosclerosis and other inflammatory and/or immunological disorders.
Public/Granted literature
Information query
