Invention Grant
- Patent Title: Culture for expanding stem cells ex-vivo
- Patent Title (中): 文化扩张干细胞离体
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Application No.: US12668818Application Date: 2008-07-09
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Publication No.: US09206389B2Publication Date: 2015-12-08
- Inventor: Lorenza Lazzari , Tiziana Montemurro , Rosaria Giordano , Paolo Rebulla , Girolamo Sirchia
- Applicant: Lorenza Lazzari , Tiziana Montemurro , Rosaria Giordano , Paolo Rebulla , Girolamo Sirchia
- Applicant Address: IT Milan
- Assignee: Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico
- Current Assignee: Fondazione IRCCS Ca' Granda-Ospedale Maggiore Policlinico
- Current Assignee Address: IT Milan
- Agency: Silvia Salvadori, P.C.
- Agent Silvia Salvadori
- Priority: ITMI2007A1421 20070716
- International Application: PCT/IB2008/001798 WO 20080709
- International Announcement: WO2009/010841 WO 20090122
- Main IPC: C12N5/00
- IPC: C12N5/00 ; C12N5/073 ; C12N5/078 ; A61K35/12
Abstract:
The present invention relates to a culture including a growth medium and a combination of cytokines consisting of i) interleukin-6 (IL6); ii) flt3-ligand (FLT3); iii) stem cell factor (SCF) and iv) thrombopoi-etin (TPO); the use of the culture for expanding. ex vivo stem cells and/or parental cells and cells differentiated therefrom, and the use of said cells obtainable from said expansion.
Public/Granted literature
- US20100189700A1 CULTURE FOR EXPANDING STEM CELLS EX-VIVO Public/Granted day:2010-07-29
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