A locking mechanism for a communication module is provided. The locking mechanism includes a handle, a upper-and-lower bolt, a handle stopping mechanism, a handle self-locking mechanism, and a module frame on which those components are arranged; wherein the handle is connected with the upper-and-lower bolt through the linkage mechanism of the upper-and-lower bolt; when rotating under the action of a force, the handle is moved with the upper-and-lower bolt through the linkage mechanism, and the communication module is inserted into or pulled out of communication device by the elastic function of the upper-and-lower bolt; when the communication module is not inserted into the communication equipment, a stopping bolt on the handle stopping mechanism stops the handle and the handle is locked; when the communication module is inserted, the stopping bolt separates from and releases the handle and the handle is self-locked. The locking mechanism avoids mounting by screws.