Invention Grant
- Patent Title: Gamma secretase inhibitors
- Patent Title (中): γ分泌酶抑制剂
-
Application No.: US14342953Application Date: 2012-09-04
-
Publication No.: US09226927B2Publication Date: 2016-01-05
- Inventor: Wen-Lian Wu , Duane A. Burnett
- Applicant: Wen-Lian Wu , Duane A. Burnett
- Applicant Address: US NJ Rahway
- Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee: MERCK SHARP & DOHME CORP.
- Current Assignee Address: US NJ Rahway
- Agent J. Eric Thies; John C. Todaro
- International Application: PCT/US2012/053598 WO 20120904
- International Announcement: WO2013/036464 WO 20130314
- Main IPC: C07D493/04
- IPC: C07D493/04 ; A61K31/4155 ; A61K31/4245 ; A61K31/4433 ; A61K31/497 ; A61K31/501 ; A61K45/06
Abstract:
Disclosed herein are compounds of Formula (I) (I) and pharmaceutically acceptable salts thereof, wherein each of the substituents is given the definition as set forth in the specification and claims. Also disclosed are pharmaceutical compositions containing the compound of Formula (I) and use of the compound in the treatment of neurodegenerative diseases or conditions such as Alzheimer's disease.
Public/Granted literature
- US20140227302A1 GAMMA SECRETASE INHIBITORS Public/Granted day:2014-08-14
Information query
