Invention Grant
- Patent Title: Methods for treating microbial infection
- Patent Title (中): 治疗微生物感染的方法
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Application No.: US14512867Application Date: 2014-10-13
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Publication No.: US09226947B1Publication Date: 2016-01-05
- Inventor: Eric P. Skaar , Brian Corbin
- Applicant: VANDERBILT UNIVERSITY
- Applicant Address: US TN Nashville
- Assignee: Vanderbilt University
- Current Assignee: Vanderbilt University
- Current Assignee Address: US TN Nashville
- Agency: Stites & Harbison PLLC
- Agent Mandy Wilson Decker
- Main IPC: C07K14/00
- IPC: C07K14/00 ; A61K38/17

Abstract:
A method for treating a microbial infection or an abscessed tissue in a subject includes administering to the subject an effective amount of a metal ion chelator. In some embodiments, the metal ion chelator can be a protein, such as a calprotectin heterodimer. In some embodiments, the metal ion chelator is a calprotectin heterodimer including an S100A8 polypeptide and an S100A9 polypeptide.
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