Invention Grant
- Patent Title: Compositions and methods of enhancing immune responses
- Patent Title (中): 增强免疫反应的组合物和方法
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Application No.: US14100957Application Date: 2013-12-09
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Publication No.: US09226957B2Publication Date: 2016-01-05
- Inventor: Walter Bottje , Billy Hargis , Luc Berghman , Young Min Kwon , Kimberly Cole , Mandy Cox , Sherryll Layton
- Applicant: THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ARKANSAS
- Applicant Address: US TX College Station US AR Little Rock
- Assignee: The Texas A&M University System,The Board of Trustees of the University of Arkansas
- Current Assignee: The Texas A&M University System,The Board of Trustees of the University of Arkansas
- Current Assignee Address: US TX College Station US AR Little Rock
- Agency: Andrus Intellectual Property Law, LLP
- Main IPC: A61K39/00
- IPC: A61K39/00 ; A61K39/02 ; A61K39/12 ; A61K39/145 ; A61K39/112 ; C12N15/10 ; C07H21/04

Abstract:
Provided herein are Salmonella enteritidis 13A strains and compositions comprising these strains. Also provided are methods of enhancing an immune response against Influenza A and methods of reducing morbidity associated with an Influenza A infection. Methods of enhancing an immune response to a vaccine vector by expressing a polypeptide of CD154 capable of binding CD40 are also disclosed. Methods of developing a bacterial vaccine vector are disclosed. Methods of generating scarless site-specific mutations in a bacterium are also disclosed.
Public/Granted literature
- US20140093534A1 COMPOSITIONS AND METHODS OF ENHANCING IMMUNE RESPONSES Public/Granted day:2014-04-03
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