Invention Grant
- Patent Title: Antiproliferative compounds, conjugates thereof, methods therefor, and uses thereof
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Application No.: US14324480Application Date: 2014-07-07
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Publication No.: US09226974B2Publication Date: 2016-01-05
- Inventor: Heng Cheng , Sanjeev Gangwar , Qiang Cong
- Applicant: E. R. Squibb & Sons, L.L.C.
- Applicant Address: US NJ Princeton
- Assignee: E. R. SQUIBB & SONS, L.L.C.
- Current Assignee: E. R. SQUIBB & SONS, L.L.C.
- Current Assignee Address: US NJ Princeton
- Agent Yuan Chao
- Main IPC: A61K39/395
- IPC: A61K39/395 ; A61K47/48 ; C07K5/02 ; C07K5/078 ; C07K5/10 ; C07K16/18 ; C07C229/14 ; C07C229/16 ; A61K38/06
Abstract:
Antiproliferative compounds having a structure represented by formula (II), where n, R1, R2, R3, R4, and R5 are as defined herein, can be used to treat tumors, optionally when conjugated to a ligand such as an antibody:
Public/Granted literature
- US20140323690A1 ANTIPROLIFERATIVE COMPOUNDS, CONJUGATES THEREOF, METHODS THEREFOR, AND USES THEREOF Public/Granted day:2014-10-30
Information query
