Invention Grant
- Patent Title: Antiviral phosphonate analogues and process for preparation thereof
- Patent Title (中): 抗病毒膦酸酯类似物及其制备方法
-
Application No.: US14439578Application Date: 2013-10-29
-
Publication No.: US09227990B2Publication Date: 2016-01-05
- Inventor: Manjinder Singh Phull , Rajendra Narayanrao Kankan , Dharmaraj Ramachandra Rao
- Applicant: Cipla Limited
- Applicant Address: IN Mumbai
- Assignee: CIPLA LIMITED
- Current Assignee: CIPLA LIMITED
- Current Assignee Address: IN Mumbai
- Agency: Conley Rose, P.C.
- Agent Rodney B. Carroll
- Priority: IN3132/MUM/2012 20121029
- International Application: PCT/GB2013/000461 WO 20131029
- International Announcement: WO2014/068265 WO 20140508
- Main IPC: C07D293/06
- IPC: C07D293/06 ; C07H21/00 ; C07F9/6561
Abstract:
The present invention provides a compound of the Formula (I) wherein R is 9-isopropyl-9H-purin-6-amine; 2-amino-9-isopropyl-1H-purin-6(9H)-one; 4-amino-1-isopropyl pyrimidin-2(1H)-one; or 1-isopropyl-5-methylpyrimidine-2,4(1H,3H)-dione, R′ is —CH2OC(O)R″, and R″ is —C(CH3)3 or —CH(CH3)2 including pharmaceutically acceptable salts thereof. The present invention also provides a process for preparing a compound of formula (Ia) and a compound of formula (I) for use in treating a viral infection.
Public/Granted literature
- US20150291639A1 Antiviral Phosphonate Analogues and Process for Preparation Thereof Public/Granted day:2015-10-15
Information query
