Invention Grant
- Patent Title: Mutants of cholesterol-dependent cytolysins and uses thereof
- Patent Title (中): 胆固醇依赖性细胞溶质蛋白的突变体及其用途
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Application No.: US13401460Application Date: 2012-02-21
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Publication No.: US09228001B2Publication Date: 2016-01-05
- Inventor: Rodney K. Tweten
- Applicant: Rodney K. Tweten
- Applicant Address: US OK Norman
- Assignee: The Board of Regents of the University of Oklahoma
- Current Assignee: The Board of Regents of the University of Oklahoma
- Current Assignee Address: US OK Norman
- Main IPC: C12N5/10
- IPC: C12N5/10 ; A61K39/02 ; C12N1/21 ; C12N1/15 ; C12N1/19 ; C12N15/63 ; C07K14/33 ; C07K14/32 ; C07H21/04 ; A61K39/08 ; A61K39/07 ; C07K14/315 ; A61K39/09 ; C07K14/195 ; C12N7/01 ; C07K14/31 ; A61K38/00 ; A61K39/00
Abstract:
Mutants of cholesterol-dependent cytolysins comprising at least one amino acid substitution in at least one of Loop 1, Loop 2, or Loop 3 of Domain 4, nucleic acids, vectors, and host cells encoding such polypeptide mutants, and compositions and vaccines comprising such polypeptide mutants.
Public/Granted literature
- US20120148624A1 MUTANTS OF CHOLESTEROL-DEPENDENT CYTOLYSINS AND USES THEREOF Public/Granted day:2012-06-14
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