Invention Grant
- Patent Title: Complement factor B analogs and their uses
- Patent Title (中): 补体因子B类似物及其用途
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Application No.: US14115115Application Date: 2012-05-04
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Publication No.: US09228003B2Publication Date: 2016-01-05
- Inventor: ChangHung Chen , Michael Kaleko , Beibei Li , Tianci Luo , Jeffrey Allan Miller , Ruigong Wang
- Applicant: ChangHung Chen , Michael Kaleko , Beibei Li , Tianci Luo , Jeffrey Allan Miller , Ruigong Wang
- Applicant Address: US MD Gaithersburg
- Assignee: Wellstat Immuno Therapeutics, LLC
- Current Assignee: Wellstat Immuno Therapeutics, LLC
- Current Assignee Address: US MD Gaithersburg
- Agent Lewis J. Kreisler
- International Application: PCT/US2012/036459 WO 20120504
- International Announcement: WO2012/151468 WO 20121108
- Main IPC: C07K14/47
- IPC: C07K14/47 ; C07K16/18 ; C07K16/40 ; C12N9/64
Abstract:
The invention provides polypeptides comprising a complement factor B analog. The invention also provides various complement factor B analogs including complement factor B analogs comprising a mutation of a free cysteine amino acid and related methods, nucleic acids and vectors. These complement factor B analogs and related methods, nucleic acids and vectors can be used to modulate a complement pathway or for the study and/or treatment of various conditions or diseases related to a complement pathway.
Public/Granted literature
- US20140249072A1 COMPLEMENT FACTOR B ANALOGS AND THEIR USES Public/Granted day:2014-09-04
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