Invention Grant
US09228011B2 Antibodies against the S100P protein for the treatment and diagnosis of cancer
有权
针对S100P蛋白的抗癌治疗和诊断抗体
- Patent Title: Antibodies against the S100P protein for the treatment and diagnosis of cancer
- Patent Title (中): 针对S100P蛋白的抗癌治疗和诊断抗体
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Application No.: US13985121Application Date: 2012-01-17
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Publication No.: US09228011B2Publication Date: 2016-01-05
- Inventor: José Luis Hernández Míguez , Jaume Adan Plana , Josep Maria Martínez Escolà , Marc Masa Álvarez , Ramon Messeguer Peypoch , Francesc Mitjans Prat , Sheila Dakhel Plaza , Antonio Coll Manzano , Rosa Ma Hervas Villegas , Carme Calvis Calpe , Laura Padilla García , Lourdes Tatiana Roque Navarro , Laura Barberà Ferrando , Manuel Rivas Cañas
- Applicant: José Luis Hernández Míguez , Jaume Adan Plana , Josep Maria Martínez Escolà , Marc Masa Álvarez , Ramon Messeguer Peypoch , Francesc Mitjans Prat , Sheila Dakhel Plaza , Antonio Coll Manzano , Rosa Ma Hervas Villegas , Carme Calvis Calpe , Laura Padilla García , Lourdes Tatiana Roque Navarro , Laura Barberà Ferrando , Manuel Rivas Cañas
- Applicant Address: ES Barcelona
- Assignee: Lykera Biomed SA
- Current Assignee: Lykera Biomed SA
- Current Assignee Address: ES Barcelona
- Agency: Greer, Burns & Crain, Ltd.
- Priority: EP11382010 20110117
- International Application: PCT/EP2012/050653 WO 20120117
- International Announcement: WO2012/098124 WO 20120726
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/18 ; C07K14/47 ; C07K16/24 ; C12R1/91 ; A61K31/704 ; G01N33/574 ; A61K39/00
Abstract:
The present invention relates to the use of antibodies against the S100P protein for the prevention and/or treatment of cancer; and to methods and kits for diagnosing cancer in vitro by means of detecting the levels of S100P in a biofluid, preferably with an antibody. The invention also relates to specific anti-S100P monoclonal antibodies, hybridoma cell lines producing them and method for obtaining them, as well as to pharmaceutical compositions and conjugates containing them.
Public/Granted literature
- US20140050734A1 ANTIBODIES AGAINST THE S100P PROTEIN FOR THE TREATMENT AND DIAGNOSIS OF CANCER Public/Granted day:2014-02-20
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