Invention Grant
US09228014B2 Antibodies capable of blocking the interaction between CD48 and a CD48 receptor
有权
能够阻断CD48与CD48受体之间相互作用的抗体
- Patent Title: Antibodies capable of blocking the interaction between CD48 and a CD48 receptor
- Patent Title (中): 能够阻断CD48与CD48受体之间相互作用的抗体
-
Application No.: US13244960Application Date: 2011-09-26
-
Publication No.: US09228014B2Publication Date: 2016-01-05
- Inventor: Brendan J. Classon , Ana Kostic , Xunbao Duan
- Applicant: Brendan J. Classon , Ana Kostic , Xunbao Duan
- Applicant Address: US NY Tarrytown
- Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee: Regeneron Pharmaceuticals, Inc.
- Current Assignee Address: US NY Tarrytown
- Agency: Merchant & Gould, P.C.
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; A61K39/00
Abstract:
The present invention provides antibodies that bind to CD48 and methods of using same. According to certain embodiments of the invention, the antibodies are fully human antibodies that bind to human CD48. In certain embodiments, the antibodies of the present invention block the binding of CD48 to one or more CD48 receptor. The antibodies of the invention are useful, inter alia, for the treatment of diseases and disorders associated with one or more CD48 biological activities, including the treatment of allergic conditions and other inflammatory conditions.
Public/Granted literature
- US20120076790A1 ANTI-CD48 ANTIBODIES AND USES THEREOF Public/Granted day:2012-03-29
Information query
