Invention Grant
- Patent Title: Compositions and methods for diagnosing and treating cancer
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Application No.: US13826103Application Date: 2013-03-14
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Publication No.: US09228020B2Publication Date: 2016-01-05
- Inventor: Austin L. Gurney , Fumiko Takada Axelrod , Timothy Charles Hoey , Sanjeev H. Satyal
- Applicant: OncoMed Pharmaceuticals, Inc.
- Applicant Address: US CA Redwood City
- Assignee: OncoMed Pharmaceuticals, Inc.
- Current Assignee: OncoMed Pharmaceuticals, Inc.
- Current Assignee Address: US CA Redwood City
- Agency: Sterne, Kessler, Goldstein & Fox PLLC
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/30 ; A61K45/06 ; A61K39/00
Abstract:
An isolated antibody that specifically binds to an extracellular domain of human DLL4 and affects growth of a tumor comprising cancer stem cells is described. Also described is a method of treating cancer comprising administering a therapeutically effective amount of an anti-DLL4 antibody.
Public/Granted literature
- US20140147443A9 COMPOSITIONS AND METHODS FOR DIAGNOSING AND TREATING CANCER Public/Granted day:2014-05-29
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