Invention Grant
- Patent Title: Human toll-like receptor inhibitors and methods of use thereof
- Patent Title (中): 人类toll样受体抑制剂及其使用方法
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Application No.: US13842861Application Date: 2013-03-15
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Publication No.: US09228184B2Publication Date: 2016-01-05
- Inventor: Cristiana Guiducci , Karen L. Fearon , Franck Barrat
- Applicant: Dynavax Technologies Corporation
- Applicant Address: US CA Berkeley
- Assignee: Dynavax Technologies Corporation
- Current Assignee: Dynavax Technologies Corporation
- Current Assignee Address: US CA Berkeley
- Agency: Morrison & Foerster LLP
- Main IPC: C12N15/117
- IPC: C12N15/117 ; A61K31/7115 ; A61K31/712 ; C07H21/04 ; C07H21/02 ; A61K31/711 ; A61K31/7125 ; A61K31/713 ; C12N15/11
Abstract:
Provided herein are human Toll-like receptor (TLR)-inhibitors and methods for use in individuals having an autoimmune disease or an inflammatory disorder. The TLR inhibitors of the present disclosure are polynucleotides comprising an inhibitory motif for one or more of TLR7, TLR8 and TLR9.
Public/Granted literature
- US20140094504A1 HUMAN TOLL-LIKE RECEPTOR INHIBITORS AND METHODS OF USE THEREOF Public/Granted day:2014-04-03
Information query
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