Invention Grant
- Patent Title: Method for assaying OGFOD1 activity
- Patent Title (中): OGFOD1活性测定方法
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Application No.: US13985243Application Date: 2012-02-10
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Publication No.: US09228224B2Publication Date: 2016-01-05
- Inventor: Christopher Joseph Schofield , Alexander Wolf , Wei Ge , Armin Thalhammer , Christoph Loenarz , Peter John Ratcliffe , Matthew Edward Cockman
- Applicant: Christopher Joseph Schofield , Alexander Wolf , Wei Ge , Armin Thalhammer , Christoph Loenarz , Peter John Ratcliffe , Matthew Edward Cockman
- Applicant Address: GB Oxford
- Assignee: ISIS INNOVATION LIMITED
- Current Assignee: ISIS INNOVATION LIMITED
- Current Assignee Address: GB Oxford
- Agency: Clark & Elbing LLP
- Agent Susan M. Michaud
- Priority: GB1102659.8 20110215
- International Application: PCT/GB2012/050303 WO 20120210
- International Announcement: WO2012/110789 WO 20120823
- Main IPC: C12Q1/26
- IPC: C12Q1/26
Abstract:
The present invention relates to assays for monitoring activity of OGFOD1 activity, in particular, to assays for identifying modulators of OGFOD1 activity. The invention also relates to assays to monitor the prolyl hydroxylase activity of OGFOD1 on its substrate, the human ribosomal protein RPS23. The invention also enables the introduction of 3-hydroxyprolyl residues into peptides and proteins.
Public/Granted literature
- US20140051106A1 METHOD FOR ASSAYING OGFOD1 ACTIVITY Public/Granted day:2014-02-20
Information query
