A sweatband for use on the hand and wrist is provided. The sweatband provides a surface on the back of a user's hand which may be utilized by a person to wipe sweat or perspiration. Thus, the back of the hand (opisthenar or dorsal surface of the hand) is used when wiping perspiration. The sweatband is constructed such that a first band portion wraps around a user's wrist and a second band portion wraps around the palm and back portion of a user's hand. In one embodiment the sweatband may be constructed of an elongated piece of material that is looped to form the first and second band portions. In one embodiment, a sweatband is interchangeable for use with the left or right hand. In one embodiment the sweatband is reversible.