Invention Grant
US09242945B2 Substituted 2-benzylidene-2H-benzo[b][1,4]thiazin-3(4H)-ones, derivatives thereof, and therapeutic uses thereof
有权
取代的2-亚苄基-2H-苯并[b] [1,4]噻嗪-3（4H） - 酮及其衍生物及其治疗用途
![Substituted 2-benzylidene-2H-benzo[b][1,4]thiazin-3(4H)-ones, derivatives thereof, and therapeutic uses thereof](/docs/US/2016-01-26/US09242945B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted 2-benzylidene-2H-benzo[b][1,4]thiazin-3(4H)-ones, derivatives thereof, and therapeutic uses thereof
- Patent Title (中): 取代的2-亚苄基-2H-苯并[b] [1,4]噻嗪-3（4H） - 酮及其衍生物及其治疗用途
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Application No.: US14090350Application Date: 2013-11-26
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Publication No.: US09242945B2Publication Date: 2016-01-26
- Inventor: E. Premkumar Reddy , M. V. Ramana Reddy
- Applicant: E. Premkumar Reddy , M. V. Ramana Reddy
- Applicant Address: US PA Philadelphia
- Assignee: TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
- Current Assignee: TEMPLE UNIVERSITY—OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
- Current Assignee Address: US PA Philadelphia
- Agency: Drinker Biddle & Reath LLP
- Main IPC: C07D279/16
- IPC: C07D279/16 ; C07D417/06 ; C07D417/10 ; C07D279/20 ; A61K47/48
![Substituted 2-benzylidene-2H-benzo[b][1,4]thiazin-3(4H)-ones, derivatives thereof, and therapeutic uses thereof](/abs-image/US/2016/01/26/US09242945B2/abs.jpg.150x150.jpg)
Abstract:
The present invention relates to compounds according to Formula I: and salts thereof, wherein R1, R2, R3, R4, Ar, and n are as defined herein. Methods for preparing compounds of Formula I are also provided. The present invention further includes methods of treating cellular proliferative disorders, such as cancer, with the compounds of Formula I.
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