Invention Grant
- Patent Title: Lactam derivatives useful as orexin receptor antagonists
- Patent Title (中): 用作食欲素受体拮抗剂的内酰胺衍生物
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Application No.: US13884741Application Date: 2011-11-09
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Publication No.: US09242970B2Publication Date: 2016-01-26
- Inventor: Hamed Aissaoui , Christoph Boss , Christine Brotschi , Bibia Heidmann , Thierry Sifferlen , Jodi T. Williams
- Applicant: Hamed Aissaoui , Christoph Boss , Christine Brotschi , Bibia Heidmann , Thierry Sifferlen , Jodi T. Williams
- Applicant Address: CH Allschwil
- Assignee: ACTELION PHARMACEUTICALS LTD.
- Current Assignee: ACTELION PHARMACEUTICALS LTD.
- Current Assignee Address: CH Allschwil
- Agency: Hoxie & Associates, LLC
- Priority: WOPCT/IB2010/055105 20101110
- International Application: PCT/IB2011/054993 WO 20111109
- International Announcement: WO2012/063207 WO 20120518
- Main IPC: A61K31/365
- IPC: A61K31/365 ; C07D413/10 ; C07D207/26 ; C07D207/273 ; C07D211/76 ; C07D215/08 ; C07D215/14 ; C07D223/10 ; C07D241/06 ; C07D401/06 ; C07D401/10 ; C07D401/14 ; C07D405/06 ; C07D405/14 ; C07D407/04 ; C07D409/06 ; C07D413/06 ; C07D417/06 ; C07D417/10 ; C07D417/14
Abstract:
The present invention relates to lactam derivatives of formula (I) wherein Y, R1, R2 and R3 are as described in the description, to their preparation, to pharmaceutically acceptable salts thereof, and to their use as pharmaceuticals, to pharmaceutical compositions containing one or more compounds of formula (I), and especially to their use as orexin receptor antagonists.
Public/Granted literature
- US20130237525A1 LACTAM DERIVATIVES USEFUL AS OREXIN RECEPTOR ANTAGONISTS Public/Granted day:2013-09-12
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