Invention Grant
US09243014B2 Method of treatment with prodrugs of 6-cyclohexyl-1-hydroxy-4-methylpyridin in-2-1H-one and derivatives thereof
有权
6-环己基-1-羟基-4-甲基吡啶在2-1H-酮中的前体药物及其衍生物的治疗方法
- Patent Title: Method of treatment with prodrugs of 6-cyclohexyl-1-hydroxy-4-methylpyridin in-2-1H-one and derivatives thereof
- Patent Title (中): 6-环己基-1-羟基-4-甲基吡啶在2-1H-酮中的前体药物及其衍生物的治疗方法
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Application No.: US14059287Application Date: 2013-10-21
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Publication No.: US09243014B2Publication Date: 2016-01-26
- Inventor: Mehmet Tanol , Scott J. Weir
- Applicant: Mehmet Tanol , Scott J. Weir
- Applicant Address: US KS Lawrence
- Assignee: The University of Kansas
- Current Assignee: The University of Kansas
- Current Assignee Address: US KS Lawrence
- Agency: Maschoff Brennan, PLLC
- Main IPC: A61K31/675
- IPC: A61K31/675 ; A01N57/00 ; C07F9/6596 ; C07F9/09 ; C07F9/11 ; C07F9/58 ; C07F9/59
Abstract:
A prodrug can have a structure of Formula 10 or derivative thereof or stereoisomer thereof or pharmaceutically acceptable salt thereof. The prodrug can be included in a pharmaceutical composition for use in treatment of fungus, cancer, dermatitis, superficial mycoses; inflammation, tinea pedis, tinea cruris, and tinea corporis, Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, and Microsporum canis, candidiasis (moniliasis), Candida albicans, tinea (pityriasis) vesicolor, Malassezia furfur, acute myeloid leukemia, acute lymphoid leukemia, chronic myelogenous leukemia, lymphoma or multiple myeloma.
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