Invention Grant
- Patent Title: Osteoarthritis treatment
- Patent Title (中): 骨关节炎治疗
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Application No.: US13140467Application Date: 2009-12-21
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Publication No.: US09243061B2Publication Date: 2016-01-26
- Inventor: John Allan Hamilton , Andrew David Cook
- Applicant: John Allan Hamilton , Andrew David Cook
- Applicant Address: AU
- Assignee: University of Melbourne
- Current Assignee: University of Melbourne
- Current Assignee Address: AU
- Agency: Ropes & Gray LLP
- International Application: PCT/AU2009/001672 WO 20091221
- International Announcement: WO2010/071924 WO 20100701
- Main IPC: C07K16/24
- IPC: C07K16/24 ; A61K39/395 ; A61K39/00
Abstract:
The present invention relates generally to a method for the treatment and/or prophylaxis of osteoarthritis (OA). In accordance with the present invention, an antagonist of GM-CSF can be effective in the treatment of osteoarthritis. An antagonist of GM-CSF includes, but is not limited to, an antibody that is specific for GM-CSF or the GM-CSF receptor. The present invention further provides transgenic animals, such as a GM-CSF knock-out mouse, useful for testing antagonists in certain disease models.
Public/Granted literature
- US20120003234A1 Osteoarthritis treatment Public/Granted day:2012-01-05
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