Invention Grant
US09243068B2 Combination of SEMA-4D inhibitors and immunomodulators to inhibit tumors and metastases
有权
组合SEMA-4D抑制剂和免疫调节剂抑制肿瘤和转移
- Patent Title: Combination of SEMA-4D inhibitors and immunomodulators to inhibit tumors and metastases
- Patent Title (中): 组合SEMA-4D抑制剂和免疫调节剂抑制肿瘤和转移
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Application No.: US14310848Application Date: 2014-06-20
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Publication No.: US09243068B2Publication Date: 2016-01-26
- Inventor: Elizabeth E. Evans , Ernest S. Smith , Maurice Zauderer
- Applicant: Vaccinex, Inc.
- Applicant Address: US NY Rochester
- Assignee: VACCINEX, INC.
- Current Assignee: VACCINEX, INC.
- Current Assignee Address: US NY Rochester
- Agency: Thompson Coburn LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/395 ; C07K16/40 ; A61K31/675 ; C07K16/32 ; A61K39/00
Abstract:
Provided herein are methods for inhibiting, delaying, or reducing tumor growth and metastases of plexin-B1-expressing cancer cells in a subject, comprising administering to the subject an effective amount of an isolated binding molecule which specifically binds to semaphorin-4D (SEMA4D) in combination with an effective amount of at least one other immune modulating therapy.
Public/Granted literature
- US20150044219A1 Combination of SEMA-4D Inhibitors and Immunomodulators to Inhibit Tumors and Metastases Public/Granted day:2015-02-12
Information query
