Invention Grant
- Patent Title: Insecticidal proteins
- Patent Title (中): 杀虫蛋白
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Application No.: US13499102Application Date: 2010-09-27
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Publication No.: US09243262B2Publication Date: 2016-01-26
- Inventor: Yan Gao , Jared Conville , Jeng Shong Chen
- Applicant: Yan Gao , Jared Conville , Jeng Shong Chen
- Applicant Address: CH Basel
- Assignee: Syngenta Participations AG
- Current Assignee: Syngenta Participations AG
- Current Assignee Address: CH Basel
- Agent Gregory W. Warren
- International Application: PCT/US2010/050369 WO 20100927
- International Announcement: WO2011/041256 WO 20110407
- Main IPC: C12N15/32
- IPC: C12N15/32 ; C12N15/82 ; C07K14/325

Abstract:
Improved compositions and methods for controlling pests are disclosed. In particular, novel engineered Cry1Ba (eCry1Ba) proteins having improved toxicity to lepidopteran insect pests are provided. By substituting at least one amino acid in domain I of a Cry1Ba protein an engineered Cry1Ba protein having substantially altered insecticidal properties is designed. Further, a method of making the engineered Cry1Ba proteins and methods of using the ecry1Ba nucleic acid sequences, for example in transgenic plants to express eCry1B proteins to confer protection from insect damage are disclosed.
Public/Granted literature
- US20120210464A1 INSECTICIDAL PROTEINS Public/Granted day:2012-08-16
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