Invention Grant
- Patent Title: Steroidal ligands and their use in gene switch modulation
-
Application No.: US13947631Application Date: 2013-07-22
-
Publication No.: US09243263B2Publication Date: 2016-01-26
- Inventor: Robert E. Hormann , Silvia Lapenna , Laurence Neil Dinan
- Applicant: Intrexon Corporation
- Applicant Address: US VA Blacksburg
- Assignee: Intrexon Corporation
- Current Assignee: Intrexon Corporation
- Current Assignee Address: US VA Blacksburg
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Main IPC: A61K31/575
- IPC: A61K31/575 ; C07C13/66 ; C07C49/753 ; C07C49/727 ; C12N15/85 ; C07J9/00 ; C07K14/705
Abstract:
The present invention relates to steroidal ligands for use in nuclear receptor-based inducible gene expression systems. The invention further relates to methods of modulating the expression of genes of interest with a system containing one or more nuclear receptor complexes and one or more steroidal ligands. Further aspects include ligand compositions including therapeutic compositions.
Public/Granted literature
- US20140057349A1 Steroidal Ligands and Their Use in Gene Switch Modulation Public/Granted day:2014-02-27
Information query
