Invention Grant
US09244059B2 Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
有权
细胞毒性抗LAG-3单克隆抗体及其在治疗或预防器官移植排斥反应和自身免疫疾病中的应用
- Patent Title: Cytotoxic anti-LAG-3 monoclonal antibody and its use in the treatment or prevention of organ transplant rejection and autoimmune disease
- Patent Title (中): 细胞毒性抗LAG-3单克隆抗体及其在治疗或预防器官移植排斥反应和自身免疫疾病中的应用
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Application No.: US12823795Application Date: 2010-06-25
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Publication No.: US09244059B2Publication Date: 2016-01-26
- Inventor: Frederic Triebel , Bernard Vanhove , Thomas Haudebourg
- Applicant: Frederic Triebel , Bernard Vanhove , Thomas Haudebourg
- Applicant Address: FR Orsay FR Paris
- Assignee: Immutep Parc Club Orsay,Inserm—Institut National De La Sante Et De La Recherche Medicale
- Current Assignee: Immutep Parc Club Orsay,Inserm—Institut National De La Sante Et De La Recherche Medicale
- Current Assignee Address: FR Orsay FR Paris
- Agent Margaret M. Tomaska; Edward R. Gimmi
- Priority: EP07290545 20070430
- Main IPC: G01N33/50
- IPC: G01N33/50 ; C07K16/28 ; A61K39/00
Abstract:
Cytotoxic anti-LAG-3 monoclonal antibodies or fragments thereof causing depletion of LAG-3+ activated T cells are described, as are related pharmaceuticals and methods of treating. Also described are related nucleic acid and protein sequences.
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