Invention Grant
- Patent Title: Production of tissue engineered heart valves
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Application No.: US11373066Application Date: 2006-03-10
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Publication No.: US09248015B2Publication Date: 2016-02-02
- Inventor: Anthony Atala , James Yoo
- Applicant: Anthony Atala , James Yoo
- Applicant Address: US NC Winston-Salem
- Assignee: Wake Forest University Health Services
- Current Assignee: Wake Forest University Health Services
- Current Assignee Address: US NC Winston-Salem
- Agency: Pepper Hamilton LLP
- Agent Thomas J. Engellenner; Reza Mollaaghababa
- Main IPC: A61F2/24
- IPC: A61F2/24 ; A61L27/36 ; A61L27/38 ; B82Y5/00 ; B82Y10/00 ; A61L27/50

Abstract:
The invention is directed to methods for preparing artificial heart valves by preconditioning a matrix seeded with endothelial cells and smooth muscle cells differentiated from isolated progenitor cells. These cell seeded matrices are exposed to fluid conditions that mimic blood flow through the heart to produce tissue engineered heart valves that are analogous to native heart valves.
Public/Granted literature
- US20060253192A1 Production of tissue engineered heart valves Public/Granted day:2006-11-09
Information query
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