Invention Grant
- Patent Title: Reversing intestinal inflammation by inhibiting retinoic acid metabolism
- Patent Title (中): 通过抑制视黄酸代谢来逆转肠道炎症
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Application No.: US13592180Application Date: 2012-08-22
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Publication No.: US09248120B2Publication Date: 2016-02-02
- Inventor: Hweixian Leong Penny , Edgar G. Engleman
- Applicant: Hweixian Leong Penny , Edgar G. Engleman
- Applicant Address: US CA Stanford
- Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Current Assignee: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
- Current Assignee Address: US CA Stanford
- Agency: Bozicevic, Field & Francis LLP
- Agent Kyle A. Gurley
- Main IPC: A61K31/428
- IPC: A61K31/428 ; A61K31/4184
Abstract:
An agent that increases local concentration of retinoic acid (RA) in the intestine through modifying enzymatic pathways involved in RA metabolism is administered in a dose effective to inhibit or reverse production of inflammatory mediators by intestinal dendritic cells and thereby reduce intestinal inflammation and tumor growth associated with intestinal inflammation.
Public/Granted literature
- US20130131129A1 Reversing Intestinal Inflammation by Inhibiting Retinoic Acid Metabolism Public/Granted day:2013-05-23
Information query
IPC分类:
