Invention Grant
- Patent Title: Insulin-like growth factor binding protein 7 for treatment of cancer
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Application No.: US14094042Application Date: 2013-12-02
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Publication No.: US09248163B2Publication Date: 2016-02-02
- Inventor: Michael Green , Narendra Wajapeyee
- Applicant: University of Massachusetts
- Applicant Address: US MA Boston
- Assignee: University of Massachusetts
- Current Assignee: University of Massachusetts
- Current Assignee Address: US MA Boston
- Agency: Fish & Richardson P.C.
- Main IPC: A61K41/00
- IPC: A61K41/00 ; C12Q1/68 ; C07H21/04 ; C12N5/02 ; A61K38/17 ; G01N33/574
Abstract:
Methods of treating a tumor in a subject include identifying a subject having, at risk for, or suspected of having a tumor, and administering to the subject an effective amount of an IGFBP7 agent if the tumor has increased Ras-BRAF-MEK-Erk signaling, is dependent for growth and/or survival upon the Ras-BRAF-MEK-Erk signaling pathway, and/or expresses an activated or oncogenic BRAF or RAS.
Public/Granted literature
- US20140178339A1 INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 7 FOR TREATMENT OF CANCER Public/Granted day:2014-06-26
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