Invention Grant
- Patent Title: Methods and means for the production of Ig-like molecules
- Patent Title (中): 用于产生Ig样分子的方法和方法
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Application No.: US13866756Application Date: 2013-04-19
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Publication No.: US09248182B2Publication Date: 2016-02-02
- Inventor: Cornelis A. De Kruif , Linda Johanna Aleida Hendriks , Ton Logtenberg
- Applicant: Merus B.V.
- Applicant Address: NL Utrecht
- Assignee: Merus B.V.
- Current Assignee: Merus B.V.
- Current Assignee Address: NL Utrecht
- Agency: Nelson Mullins Riley & Scarborough LLP
- Agent Jane E. Remillard, Esq.; Cynthia L. Kanik
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C12N5/07 ; C12P21/04 ; A61K39/395 ; C07K16/12 ; C07K16/26 ; C07K16/36 ; C07K16/46 ; C07K16/18 ; C12P21/00 ; C07K16/28 ; A61K39/40 ; A61K39/00
Abstract:
The invention provides means and methods for producing one or more Ig-like molecules in a single host cell. Novel CH3 mutations enabling the production of monospecific and/or bispecific Ig-like molecules of interest are also provided.
Public/Granted literature
- US20140072579A1 METHODS AND MEANS FOR THE PRODUCTION OF IG-LIKE MOLECULES Public/Granted day:2014-03-13
Information query
IPC分类:
