Invention Grant
- Patent Title: Modulators of ATP-binding cassette transporters
- Patent Title (中): ATP结合盒转运蛋白的调节剂
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Application No.: US14506856Application Date: 2014-10-06
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Publication No.: US09249131B2Publication Date: 2016-02-02
- Inventor: Sara S. Hadida Ruah , Mark T. Miller , Ashvani K. Singh , Thomas Cleveland , Lewis R. Makings , Matthew Hamilton , Peter D. J. Grootenhuis
- Applicant: Vertex Pharmaceuticals Incorporated
- Applicant Address: US MA Boston
- Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee: Vertex Pharmaceuticals Incorporated
- Current Assignee Address: US MA Boston
- Agent Michael J. DiVerdi
- Main IPC: C07D277/46
- IPC: C07D277/46 ; C07D417/06 ; C07D263/48 ; C07D277/82 ; C07D417/04 ; C07D417/12 ; C07D295/15 ; G01N33/50
Abstract:
The present invention relates to modulator of ATP-Binding Cassette (“ABC”) transporters or fragments thereof, including CF Transmembrane Regulator (“CFTR”), compositions thereof, and methods therewith. The present invention also relates to methods of treating ABC transporter mediated diseases using such modulators.
Public/Granted literature
- US20150025076A1 MODULATORS OF ATP-BINDING CASSETTE TRANSPORTERS Public/Granted day:2015-01-22
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