Invention Grant
US09249139B2 Indolizinone based derivatives as potential phosphodiesterase 3 (PDE3) inhibitors and a process for the preparation thereof
有权
基于Indolizinone的衍生物作为潜在的磷酸二酯酶3(PDE3)抑制剂及其制备方法
- Patent Title: Indolizinone based derivatives as potential phosphodiesterase 3 (PDE3) inhibitors and a process for the preparation thereof
- Patent Title (中): 基于Indolizinone的衍生物作为潜在的磷酸二酯酶3(PDE3)抑制剂及其制备方法
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Application No.: US14168370Application Date: 2014-01-30
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Publication No.: US09249139B2Publication Date: 2016-02-02
- Inventor: Budde Mahendar , Saidulu Mattapally , Mettu Ravinder , Sanjay Kumar Banerjee , Vaidya Jayathirtha Rao
- Applicant: COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH
- Applicant Address: IN New Delhi
- Assignee: Council of Scientific & Industrial Research
- Current Assignee: Council of Scientific & Industrial Research
- Current Assignee Address: IN New Delhi
- Agency: Abelman, Frayne & Schwab
- Priority: IN287/DEL/2013 20130201
- Main IPC: C07D221/02
- IPC: C07D221/02 ; C07D471/04

Abstract:
The present invention provides compounds of general formula A useful as potential phosphodiesterase3 (PDE3) inhibitory agents and a process for the preparation thereof. The derivatives of formula A can be employed as therapeutics in human and veterinary medicine, where they can be used, for example, for the treatment and prophylaxis of the following diseases: heart failure, dilated cardiomyopathy, platelet inhibitors, cancer and obstructive pulmonary diseases.
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