Invention Grant
- Patent Title: Substituted hydroxamic acids and uses thereof
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Application No.: US14573615Application Date: 2014-12-17
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Publication No.: US09249142B2Publication Date: 2016-02-02
- Inventor: Christopher Blackburn , Kenneth M. Gigstad , He Xu
- Applicant: Millennium Pharmaceuticals, Inc.
- Applicant Address: US MA Cambridge
- Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee: Millennium Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Millennium Pharmaceuticals, Inc.
- Main IPC: C07D471/02
- IPC: C07D471/02 ; C07D471/04 ; A61K31/4375 ; C07D215/54
Abstract:
This invention provides compounds of formula (I): wherein R1a, R1b, R1c, R1d, R2a, R2b, X1, X2, and G have values as described in the specification, useful as inhibitors of HDAC6. The invention also provides pharmaceutical compositions comprising the compounds of the invention and methods of using the compositions in the treatment of proliferative, inflammatory, infectious, neurological or cardiovascular diseases or disorders.
Public/Granted literature
- US20150105418A1 SUBSTITUTED HYDROXAMIC ACIDS AND USES THEREOF Public/Granted day:2015-04-16
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