Invention Grant
US09249145B2 Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
有权
吡唑-4-基 - 吡咯并[2,3-d]嘧啶的杂环衍生物作为甘油激酶抑制剂
![Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors](/docs/US/2016-02-02/US09249145B2/abs.jpg.600x600.jpg)
- Patent Title: Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors
- Patent Title (中): 吡唑-4-基 - 吡咯并[2,3-d]嘧啶的杂环衍生物作为甘油激酶抑制剂
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Application No.: US12872925Application Date: 2010-08-31
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Publication No.: US09249145B2Publication Date: 2016-02-02
- Inventor: James D. Rodgers , Yun-Long Li , Stacey Shepard , Haisheng Wang
- Applicant: James D. Rodgers , Yun-Long Li , Stacey Shepard , Haisheng Wang
- Applicant Address: US DE Wilmington US DE Wilmington
- Assignee: Incyte Holdings Corporation,Incyte Corporation
- Current Assignee: Incyte Holdings Corporation,Incyte Corporation
- Current Assignee Address: US DE Wilmington US DE Wilmington
- Agency: Fish & Richardson P.C.
- Main IPC: C07D487/04
- IPC: C07D487/04 ; A61K31/519 ; A61P35/00 ; A61P35/02 ; A61P35/04 ; A61K31/551 ; A61P37/06 ; A61P29/00 ; A61P17/00 ; A61P19/00
![Heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines as janus kinase inhibitors](/abs-image/US/2016/02/02/US09249145B2/abs.jpg.150x150.jpg)
Abstract:
The present invention provides heterocyclic derivatives of pyrazol-4-yl-pyrrolo[2,3-d]pyrimidines of Formula I: and pharmaceutically acceptable salts thereof, as well as their compositions and methods of use, that modulate the activity of Janus kinases (JAKs) and are useful in the treatment of diseases related to the activity of JAKs including, for example, inflammatory disorders, autoimmune disorders, cancer, and other diseases.
Public/Granted literature
- US20110059951A1 HETEROCYCLIC DERIVATIVES OF PYRAZOL-4-YL-PYRROLO[2,3-d]PYRIMIDINES AS JANUS KINASE INHIBITORS Public/Granted day:2011-03-10
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