Invention Grant
US09249200B2 Expression vector comprising a nucleotide sequence encoding a Volvox carteri light-activated ion channel protein (VChR1) and implantable device thereof
有权
包含编码Volvox carteri光活化离子通道蛋白（VChR1）的核苷酸序列及其可植入装置的表达载体
- Patent Title: Expression vector comprising a nucleotide sequence encoding a Volvox carteri light-activated ion channel protein (VChR1) and implantable device thereof
- Patent Title (中): 包含编码Volvox carteri光活化离子通道蛋白（VChR1）的核苷酸序列及其可植入装置的表达载体
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Application No.: US14301718Application Date: 2014-06-11
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Publication No.: US09249200B2Publication Date: 2016-02-02
- Inventor: Karl Deisseroth , Feng Zhang , Viviana Gradinaru
- Applicant: The Board of Trustees of the Leland Stanford Junior University
- Applicant Address: US CA Stanford
- Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee: The Board of Trustees of the Leland Stanford Junior University
- Current Assignee Address: US CA Stanford
- Agency: Bozicevic, Field & Francis, LLP
- Agent Paula A. Borden
- Main IPC: C12N15/00
- IPC: C12N15/00 ; C07K14/405 ; C12N15/79 ; C12N15/85 ; C07K14/47 ; A61N5/06 ; C12N7/00 ; A61N5/067
Abstract:
Methods, systems and devices are implemented in connection with light-responsive ion channel molecules. One such method is implemented using a light-activated ion channel molecule that responds to a light stimulus. The method includes engineering the light-activated ion channel molecule in a cell; and activating the ion channel molecule, in response to light stimulus that is provided to the ion channel molecule and that has properties that do not activate a ChR2 ion channel, to allow ions to pass through the light-activated ion channel molecule.
Public/Granted literature
- US20140358067A1 Systems, Methods and Compositions for Optical Stimulation of Target Cells Public/Granted day:2014-12-04
Information query
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