Invention Grant
- Patent Title: Heterologous intron within a signal peptide
- Patent Title (中): 信号肽内的异源内含子
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Application No.: US14134169Application Date: 2013-12-19
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Publication No.: US09249201B2Publication Date: 2016-02-02
- Inventor: Barbara Enenkel
- Applicant: Barbara Enenkel
- Applicant Address: DE Ingelheim am Rhein
- Assignee: Boehringer Ingelheim International GmbH
- Current Assignee: Boehringer Ingelheim International GmbH
- Current Assignee Address: DE Ingelheim am Rhein
- Agent Michael P. Morris; Atabak R. Royaee
- Priority: EP12199813 20121231
- Main IPC: C12P21/02
- IPC: C12P21/02 ; C07K14/47 ; C12N15/62 ; C12N15/63 ; C12N15/67 ; C12N15/85 ; C07K7/08 ; C07K16/00
Abstract:
The invention concerns the field of recombinant gene engineering. It concerns novel introns and compositions comprising such introns as well as a method to improve expression of polypeptides from nucleic acids such as cloned genes with heterologous introns, especially genes encoding antibodies and antibody derived fragments, and the production of various polypeptides in eukaryotic host cells using said novel intron sequences as heterologous introns.
Public/Granted literature
- US20140248660A1 HETEROLOGOUS INTRON WITHIN A SIGNAL PEPTIDE Public/Granted day:2014-09-04
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