Invention Grant
US09249211B2 Binding fusion proteins, binding fusion protein-drug conjugates, XTEN-drug conjugates and methods of making and using same
有权
结合融合蛋白，结合融合蛋白 - 药物偶联物，XTEN-药物共轭物及其制备和使用方法
- Patent Title: Binding fusion proteins, binding fusion protein-drug conjugates, XTEN-drug conjugates and methods of making and using same
- Patent Title (中): 结合融合蛋白，结合融合蛋白 - 药物偶联物，XTEN-药物共轭物及其制备和使用方法
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Application No.: US13631361Application Date: 2012-09-28
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Publication No.: US09249211B2Publication Date: 2016-02-02
- Inventor: Volker Schellenberger , Joshua Silverman , Chia-wei Wang , Benjamin Spink , Willem P. Stemmer , Nathan Geething
- Applicant: Amunix Operating Inc.
- Applicant Address: US CA Mountain View
- Assignee: Amunix Operating Inc.
- Current Assignee: Amunix Operating Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Wilson Sonsini Goodrich & Rosati
- Main IPC: C07K14/00
- IPC: C07K14/00 ; C07K14/81 ; C07K16/24 ; C07K16/40 ; C07K16/18 ; A61K38/00
Abstract:
The present invention relates to binding fusion protein compositions comprising targeting moieties linked to extended recombinant polypeptide (XTEN), binding fusion protein-drug conjugate compositions, and XTEN-drug conjugate compositions, isolated nucleic acids encoding the compositions and vectors and host cells containing the same, and methods of using such compositions in treatment of diseases, disorders, and conditions.
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