Invention Grant
- Patent Title: Immuno-based botulinum toxin serotype A activity assays
- Patent Title (中): 基于免疫的肉毒杆菌毒素血清型A活性测定
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Application No.: US13475553Application Date: 2012-05-18
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Publication No.: US09249216B2Publication Date: 2016-02-02
- Inventor: Ester Fernandez-Salas , Joanne Wang , Patton Garay , Lina S. Wong , D. Diane Hodges , Kei Roger Aoki
- Applicant: Ester Fernandez-Salas , Joanne Wang , Patton Garay , Lina S. Wong , D. Diane Hodges , Kei Roger Aoki
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Brigitte C. Phan; Ted A. Chan
- Main IPC: G01N33/53
- IPC: G01N33/53 ; C07K16/12 ; G01N33/68 ; G01N33/566 ; C12Q1/37 ; G01N33/50
Abstract:
The present specification discloses SNAP-25 compositions, methods of making α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, α-SNAP-25 antibodies that bind an epitope comprising a carboxyl-terminus at the P1 residue from the BoNT/A cleavage site scissile bond from a SNAP-25 cleavage product, methods of detecting BoNT/A activity, and methods of detecting neutralizing α-BoNT/A antibodies.
Public/Granted literature
- US20120225436A1 Immuno-Based Botulinum Toxin Serotype A Activity Assays Public/Granted day:2012-09-06
Information query
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