Invention Grant
- Patent Title: Antibodies directed to HER-3 and uses thereof
- Patent Title (中): 针对HER-3的抗体及其用途
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Application No.: US12365784Application Date: 2009-02-04
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Publication No.: US09249230B2Publication Date: 2016-02-02
- Inventor: Mike Rothe , Martin Treder , Eric Borges , Susanne Hartmann , Larry L. Green
- Applicant: Mike Rothe , Martin Treder , Eric Borges , Susanne Hartmann , Larry L. Green
- Applicant Address: DE Martinsried US CA Thousand Oaks
- Assignee: U3 Pharma GmbH,Amgen Inc.
- Current Assignee: U3 Pharma GmbH,Amgen Inc.
- Current Assignee Address: DE Martinsried US CA Thousand Oaks
- Agency: Chao Hadidi Stark & Barker LLP
- Agent Birgit Millauer
- Main IPC: A61K39/395
- IPC: A61K39/395 ; C07K16/28 ; C07K16/32 ; G01N33/574 ; A61K39/00
Abstract:
The present invention relates to binding proteins that bind to HER-3 and polynucleotides encoding the same. Expression vectors and host cells comprising the same for the production of the binding protein of the invention are also provided. In addition, the invention provides compositions and methods for diagnosing and treating diseases associated with HER-3 mediated signal transduction and/or its ligand heregulin.
Public/Granted literature
- US20100183631A1 Antibodies Directed to HER-3 and Uses Thereof Public/Granted day:2010-07-22
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