Invention Grant
- Patent Title: Framework selection
- Patent Title (中): 框架选择
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Application No.: US12307051Application Date: 2007-06-26
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Publication No.: US09249232B2Publication Date: 2016-02-02
- Inventor: Ralph Adams , Alastair David Griffiths Lawson , Andrew George Popplewell , Kerry Louise Tyson
- Applicant: Ralph Adams , Alastair David Griffiths Lawson , Andrew George Popplewell , Kerry Louise Tyson
- Applicant Address: BE Brussels
- Assignee: UCB BioPharma SPRL
- Current Assignee: UCB BioPharma SPRL
- Current Assignee Address: BE Brussels
- Agency: McDonnell Boehnen Hulbert & Bergoff LLP
- Priority: GB0613209.6 20060703
- International Application: PCT/GB2007/002400 WO 20070626
- International Announcement: WO2008/003931 WO 20080110
- Main IPC: C40B30/04
- IPC: C40B30/04 ; C07K16/00 ; C07K16/46
Abstract:
The present invention relates to improved methods for the selection of appropriate human acceptor framework regions for non-human (donor) antibodies and methods for obtaining humanized antibodies of high affinity using such acceptor frameworks.
Public/Granted literature
- US20090326203A1 Framework Selection Public/Granted day:2009-12-31
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