Invention Grant
US09249405B2 Factor IX polypeptide mutant, its uses and a method for its production 有权
因子IX多肽突变体,其用途及其生产方法

  • Patent Title: Factor IX polypeptide mutant, its uses and a method for its production
  • Patent Title (中): 因子IX多肽突变体,其用途及其生产方法
  • Application No.: US13063898
    Application Date: 2009-09-15
  • Publication No.: US09249405B2
    Publication Date: 2016-02-02
  • Inventor: Paolo Simioni
  • Applicant: Paolo Simioni
  • Agency: Silvia Salvadori, P.C.
  • Agent Silvia Salvadori
  • Priority: ITBO2008A0564 20080915; ITBO2009A0275 20090506
  • International Application: PCT/EP2009/061935 WO 20090915
  • International Announcement: WO2010/029178 WO 20100318
  • Main IPC: C12N9/00
  • IPC: C12N9/00 C12N9/64
Factor IX polypeptide mutant, its uses and a method for its production
Abstract:
Disclosed are a modified FIX (factor IX) polypeptide comprising a leucine, cysteine, aspartic acid, glutamic acid, histidine, lysine, asparagine, glutamine or tyrosine in position 338; pharmaceutical preparations containing said modified FIX polypeptide; a nucleotide sequence coding for the modified FIX polypeptide; and a method for producing the modified FIX polypeptide.
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