Invention Grant
- Patent Title: Bladder cancer detection composition, kit and associated methods
- Patent Title (中): 膀胱癌检测组合物，试剂盒及相关方法
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Application No.: US13617878Application Date: 2012-09-14
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Publication No.: US09249467B2Publication Date: 2016-02-02
- Inventor: Steven Goodison , Charles J. Rosser
- Applicant: Steven Goodison , Charles J. Rosser
- Agency: Saliwanchik, Lloyd & Eisenschenk
- Main IPC: G01N33/574
- IPC: G01N33/574 ; C12Q1/00 ; G01N33/68 ; C12Q1/68
Abstract:
Compositions, kits, and methods for the diagnosis, prognosis, and monitoring of bladder cancer in a subject are provided by detecting in a urine sample a combination of biomarkers. In one embodiment of the invention, a nine-biomarker panel consisting of IL-8, MMP9, SDC1, CCL18, SERPINE1, CD44, VEGF-A, CA9, and ANG may be detected. In another embodiment of the invention, a three-biomarker panel consisting of CCL18, CD44, and VEGF-A may be detected. In yet another embodiment of the invention, a nine-biomarker panel consisting of CA9, CCL18, MMP12, TMEM45A, MMP9, SEMA3D, ERBB2, CRH, and MXRA8 may be detected.
Public/Granted literature
- US20130184172A1 Bladder Cancer Detection Composition, Kit and Associated Methods Public/Granted day:2013-07-18
Information query
IPC分类:
