A system according to the principles of the present disclosure includes a vibration characteristics module and a firing pattern module. The vibration characteristics module, for a first plurality of firing patterns of an engine when a cylinder of the engine is deactivated, stores vibration characteristics associated with at least one of an amplitude, a frequency, and a phase of vibration at a driver interface component resulting from the first plurality of firing patterns. The firing pattern module selects a firing pattern from a second plurality of firing patterns and executes the firing pattern when the vibration characteristics associated with the selected firing pattern satisfies predetermined criteria.