Invention Grant
- Patent Title: Nanopore molecule detection system and molecule detection method based on potential measurement of insulated conductive thin layer
- Patent Title (中): 基于绝缘导电薄层电位测量的纳米孔分子检测系统和分子检测方法
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Application No.: US13674344Application Date: 2012-11-12
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Publication No.: US09250202B2Publication Date: 2016-02-02
- Inventor: Honggu Chun
- Applicant: SNU R&DB FOUNDATION
- Applicant Address: KR Seoul
- Assignee: SNU R&DB FOUNDATION
- Current Assignee: SNU R&DB FOUNDATION
- Current Assignee Address: KR Seoul
- Agency: Fenwick & West LLP
- Priority: KR10-2010-0045419 20100514
- Main IPC: G01N27/00
- IPC: G01N27/00 ; G01N33/487

Abstract:
A particle detector includes: a conductive nanolayer; insulating nanolayers attached to both sides of the conductive nanolayer; a nanopore formed to penetrate the conductive nanolayer and the insulating nanolayers so as to provide a migration path for a sample particle; a power supply unit configured to apply an electric field between both ends of the nanopore so as to apply a potential to the conductive nanolayer; and an electric signal measuring unit electrically connected to the conductive nanolayer and configured to measure the potential change in the conductive nanolayer induced by the sample particle as the sample particle migrates through the nanopore. The particle detector is capable of detecting a particle with high signal-to-noise ratio and resolution, scanning a sample without mechanical motion of the conductive nanolayer and analyzing DNA base sequences.
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