Invention Grant
- Patent Title: In vitro capture and analysis of circulating tumor cells
- Patent Title (中): 循环肿瘤细胞的体外捕获和分析
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Application No.: US14075143Application Date: 2013-11-08
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Publication No.: US09250242B2Publication Date: 2016-02-02
- Inventor: George Martin , Steven Soper , Makgorzata Witek , Jen Jen Yeh
- Applicant: Roche Molecular Systems, Inc. , The University of North Carolina at Chapel Hill
- Applicant Address: US CA Pleasanton US NC Chapel Hill
- Assignee: ROCHE MOLECULAR SYSTEMS, INC.,THE UNIVERSITY OF NORTH CAROLINA
- Current Assignee: ROCHE MOLECULAR SYSTEMS, INC.,THE UNIVERSITY OF NORTH CAROLINA
- Current Assignee Address: US CA Pleasanton US NC Chapel Hill
- Agent Carol Johns; Olga Kay
- Main IPC: G01N33/574
- IPC: G01N33/574 ; G01N33/569 ; B01L3/00
Abstract:
This invention provides methods and compositions for capturing circulating tumor cells (CTCs) as well as various divergent CTC phenotypes using seprase-specific affinity reagents. Methods of analyzing CTCs and assessing their metastatic potential in vivo and in vitro are also disclosed.
Public/Granted literature
- US20140134646A1 VITRO CAPTURE AND ANALYSIS OF CIRCULATING TUMOR CELLS Public/Granted day:2014-05-15
Information query
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