Invention Grant
US09250247B2 Methods of detecting antibodies specific for denatured HLA antigens
有权
检测变性HLA抗原特异性抗体的方法
- Patent Title: Methods of detecting antibodies specific for denatured HLA antigens
- Patent Title (中): 检测变性HLA抗原特异性抗体的方法
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Application No.: US14102571Application Date: 2013-12-11
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Publication No.: US09250247B2Publication Date: 2016-02-02
- Inventor: Jar-How Lee , Rui Pei , Thao Nong
- Applicant: ONE LAMBDA
- Applicant Address: US CA Canoga Park
- Assignee: ONE LAMBDA
- Current Assignee: ONE LAMBDA
- Current Assignee Address: US CA Canoga Park
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: G01N33/543
- IPC: G01N33/543 ; G01N33/68 ; G01N33/50 ; C07K16/28
Abstract:
The invention is directed to methods of screening for HLA antibodies comprising detecting antibodies specific for native HLA antigens and denatured HLA antigens. The invention also provides for methods of removing antibodies specific for denatured HLA antigens or antibodies specific for native HLA antigens from a serum sample. In addition, the invention also provides for method of predicting whether a transplant recipient has an increased risk for rejecting the transplanted organ.
Public/Granted literature
- US20140099733A1 Methods of Detecting Antibodies Specific for Denatured HLA Antigents Public/Granted day:2014-04-10
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