The present invention discloses a sealant coating equipment of a liquid crystal panel which comprises a nozzle, the nozzle is used for sealant coating of substrates required to be sealant-coated, the equipment further comprises a monitoring and detecting device. When the nozzle is performing sealant coating, the monitoring and detecting device is used for instantaneously acquiring images after the sealant coating is performed by the nozzle, determining if there are defects of sealant coating according to the acquired images, and recording location data of defective sealant coatings when determining that there are the defective sealant coatings. When the nozzle finishes the sealant coating, the monitoring and detecting device is further used for displaying images of the defective sealant coatings and locations data of the defective sealant coatings. The present invention further discloses a sealant coating method of a liquid crystal panel.