Embodiments include, but are not limited to, systems and methods for enabling Orthogonal Frequency Division Multiple Access (OFDMA) in the upstream in an Ethernet Passive Optical Network over Coax (EPoC) network. Embodiments include systems and methods for translating Ethernet Passive Optical Network (EPON) upstream time grants to OFDMA resources represented by individual subcarriers of an upstream OFDMA frame. In an embodiment, the translation of EPON upstream time grants to OFDMA resources ensures that Coaxial Network Units (CNUs) sharing an OFDMA frame do not use overlapping subcarriers within the frame. Embodiments further include systems and methods for timing upstream transmissions by the CNUs in order for the transmissions to be received within the same upstream OFDMA frame at a Fiber Coax Unit (FCU). Embodiments further include systems and methods for re-generating a data burst from OFDMA resources for transmission from the FCU to an Optical Line Terminal (OLT).