Invention Grant
US09254261B2 Stable quick dissolving dosage form comprising amoxicillin and clavulanic acid
有权
包含阿莫西林和克拉维酸的稳定快速溶解剂型
- Patent Title: Stable quick dissolving dosage form comprising amoxicillin and clavulanic acid
- Patent Title (中): 包含阿莫西林和克拉维酸的稳定快速溶解剂型
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Application No.: US14194915Application Date: 2014-03-03
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Publication No.: US09254261B2Publication Date: 2016-02-09
- Inventor: Rok Staric , Marko Oblak , Tanja Rozman Peterka , Veronika Debevec
- Applicant: Sandoz AG
- Applicant Address: CH
- Assignee: Sandoz AG
- Current Assignee: Sandoz AG
- Current Assignee Address: CH
- Agency: Luedeka Neely Group, P.C.
- Main IPC: A61K31/43
- IPC: A61K31/43 ; A61K31/424 ; A61K9/00 ; A61K47/10 ; A61K47/32 ; A61K47/02 ; A61K47/12 ; A61K9/20

Abstract:
A quick dissolving pharmaceutical formulation is disclosed. In one embodiment, the formulation includes at least the following components: (1) from about 35 to about 50 weight percent amoxicillin or a pharmaceutically acceptable salt thereof; (2) from about 2.0 to about 12 weight percent clavulanic acid or a pharmaceutically acceptable salt thereof; (3) from about 30 to about 40 weight percent mannitol; (4) from about 2 to about 7 weight percent crospovidone; (5) from about 0.5 to about 2.0 weight percent colloidal silicon dioxide; and (6) from about 2.0 to about 5.0 weight percent sodium stearyl fumarate. A method for making a quick dissolving pharmaceutical tablet is also disclosed.
Public/Granted literature
- US20150245995A1 Stable Quick Dissolving Dosage Form Comprising Amoxicillin and Clavulanic Acid Public/Granted day:2015-09-03
Information query
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