Invention Grant
US09254261B2 Stable quick dissolving dosage form comprising amoxicillin and clavulanic acid 有权
包含阿莫西林和克拉维酸的稳定快速溶解剂型

Stable quick dissolving dosage form comprising amoxicillin and clavulanic acid
Abstract:
A quick dissolving pharmaceutical formulation is disclosed. In one embodiment, the formulation includes at least the following components: (1) from about 35 to about 50 weight percent amoxicillin or a pharmaceutically acceptable salt thereof; (2) from about 2.0 to about 12 weight percent clavulanic acid or a pharmaceutically acceptable salt thereof; (3) from about 30 to about 40 weight percent mannitol; (4) from about 2 to about 7 weight percent crospovidone; (5) from about 0.5 to about 2.0 weight percent colloidal silicon dioxide; and (6) from about 2.0 to about 5.0 weight percent sodium stearyl fumarate. A method for making a quick dissolving pharmaceutical tablet is also disclosed.
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