Invention Grant
US09254274B2 Method of treating Tourette'S disorder with GABA-aminotransferase inactivators
有权
用GABA-氨基转移酶灭活剂治疗图雷特氏病的方法
- Patent Title: Method of treating Tourette'S disorder with GABA-aminotransferase inactivators
- Patent Title (中): 用GABA-氨基转移酶灭活剂治疗图雷特氏病的方法
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Application No.: US14340749Application Date: 2014-07-25
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Publication No.: US09254274B2Publication Date: 2016-02-09
- Inventor: Steven Miller , Jonathan D. Brodie , Stephen Dewey
- Applicant: CATALYST PHARMACEUTICAL PARTNERS , NEW YORK UNIVERSITY , THE FEINSTEIN INSTITUTE FOR MEDICAL RESEARCH
- Applicant Address: US FL Coral Gables US NY New York US NY Manhasset
- Assignee: Catalyst Pharmaceutical Partners, Inc.,New York University,Feinstein Institute for Medical Research
- Current Assignee: Catalyst Pharmaceutical Partners, Inc.,New York University,Feinstein Institute for Medical Research
- Current Assignee Address: US FL Coral Gables US NY New York US NY Manhasset
- Agency: Keller Life Science Law, PA
- Agent Michael J. Keller
- Main IPC: A61K31/13
- IPC: A61K31/13 ; A61K31/131 ; A61K31/195 ; A61K31/197
Abstract:
The present invention is a method of treating Tourette's Disorder (TD) using GABA ergic drugs that elevate the amount of stored presynaptic GABA and do not significantly increase GABA tone (a continuous background level of GABA signaling) in the brain. The administration of vigabatrin and/or (1S,3S)-3-amino-4-difluoromethylenyl-1-cyclopentanoic acid hydrochloride salt is expressly contemplated.
Public/Granted literature
- US20140336256A1 METHOD OF TREATING TOURETTE'S DISORDER WITH GABA-AMINOTRANSFERASE INACTIVATORS Public/Granted day:2014-11-13
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